nucleophilicity

MS 908 - SN1-SN2-E1-E2 Review Submitted by Matt on August 6, 2011.

Textbook and Chapter: Carey and Giuliano 8th Ed. (2010), Chapter 8

Keywords: leaving groups, nucleophilicity, SN1/SN2/E1/E2

Description: Goes through substitution and elimination competition reactions:

  • Nucleophile strength trends
  • Leaving group trends
  • Steric effects
  • How to tell the difference between SN1, SN2, E1, and E2 reaction conditions

Total Problems: 10

Problem # 713

When a carbonyl is treated with semicarbazide under acidic conditions an "imine" is produced called a semicarbazone.

Which of the two products below is the correct structure for a semicarbazone? Explain.

Problem # 539

Rank the following compounds in order of decreasing nucleophilicity. (1 = most nucleophilic)